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BBS4 Rekombinanter Antikörper

BBS4 Rekombinant Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

230303E4

Kat-Nr. : 82961-3-RR

Synonyme

Bardet-Biedl syndrome 4 protein, Bardet Biedl syndrome 4, 230303E4

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  • Affinity and Kinetic Characterization of 82961-3-RR

    Affinity and Kinetic Characterization of 82961-3-RR

    Biolayer interferometry (BLl) kinetic assays of 82961-3-RR against Human BBS4 were performed. The affinity constant is 0.575 nM.

Geprüfte Anwendungen

Produktinformation

82961-3-RR bindet in ELISA BBS4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen BBS4 fusion protein Ag3430
Vollständiger Name Bardet-Biedl syndrome 4
Berechnetes Molekulargewicht 519 aa, 58 kDa
GenBank-ZugangsnummerBC027624
Gene symbol BBS4
Gene ID (NCBI) 585
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BBS4 (Bardet-Biedl syndrome protein 4) is one of the early BBS proteins discovered, with 35 mutations reported to cause the BBS phenotype (PMID: 26762677). BBS4 undergoes localization to the centriolar satellites of centrosomes and basal body of primary cilia, where it takes part in recruiting cargo to centriolar satellites and allowing the formation of a functional centrosomal microtubule organizing center (MTOC) (PMID: 25860617). Some research has found that BBS4 expression in humans during the development of CNS and sensory organs, concerning the cardinal clinical signs of BBS (PMID: 33860840).