BBS5 Rekombinanter Antikörper

BBS5 Rekombinant Antikörper für WB, IF/ICC, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF/ICC, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240674B5

Kat-Nr. : 83722-1-PBS

Synonyme

240674B5, Bardet Biedl syndrome 5, Bardet-Biedl syndrome 5 protein

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  WB analysis using 83722-1-RR (same clone as 83722-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83722-1-RR (BBS5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83722-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 83722-1-RR (same clone as 83722-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83722-1-RR (BBS5 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83722-1-PBS in a different storage buffer formulation.

• 

  IF Staining of MDCK using 83722-1-RR (same clone as 83722-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MDCK cells using BBS5 antibody (83722-1-RR, Clone: 240674B5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CoraLite®594 ARL13B antibody (CL594-17711, red). This data was developed using the same antibody clone with 83722-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP00703-1

  Cytometric bead array standard curve of MP00703-1, BBS5 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83722-2-PBS. Detection antibody: 83722-1-PBS. Standard: Ag6153. Range: 2.5-80 ng/mL.

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Geprüfte Anwendungen

Produktinformation

83722-1-PBS bindet in WB, IF/ICC, Cytometric bead array, Indirect ELISA BBS5 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: BBS5 fusion protein Ag6153
• Vollständiger Name: Bardet-Biedl syndrome 5
• Berechnetes Molekulargewicht: 39 kDa
• Beobachtetes Molekulargewicht: 39 kDa
• GenBank-Zugangsnummer: BC044593
• Gene symbol: BBS5
• Gene ID (NCBI): 129880
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BBS5 encodes a protein that has been directly linked to Bardet-Biedl syndrome. Bardet-Biedl syndrome (BBS) is an autosomal recessive condition characterised by rod-cone dystrophy, postaxial polydactyly, central obesity, mental retardation, hypogonadism, and renal dysfunction. Other associated clinical findings in BBS patients include diabetes, hypertension and congenital heart defects. BBS expression varies both within and between families and diagnosis is often difficult. Experimentation in non-human eukaryotes suggests that BBS5 is expressed in ciliated cells and that it is required for the formation of cilia. Alternate transcriptional splice variants have been observed but have not been fully characterized.