BBS6 Polyklonaler Antikörper

BBS6 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13078-1-PBS

Synonyme

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  WB analysis of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse brain using 13078-1-AP (same clone as 13078-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 13078-1-AP (BBS6 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 13078-1-AP (same clone as 13078-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 13078-1-AP (BBS6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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  IF Staining of hTERT-RPE1 cells using 13078-1-AP (same clone as 13078-1-PBS)

  IF result (cytoplasm and the base of cilia stain) of anti-BBS6 (13078-1-AP; 1:50) with hTERT-RPE1 cell (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 13078-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13078-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA BBS6 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BBS6 fusion protein Ag3785
• Vollständiger Name: McKusick-Kaufman syndrome
• Berechnetes Molekulargewicht: 62 kDa
• Beobachtetes Molekulargewicht: 63 kDa
• GenBank-Zugangsnummer: BC028973
• Gene symbol: MKKS
• Gene ID (NCBI): 8195
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MKKS also known as BBS6 is a probable chaperone given to the amino acid similarity to the chaperonin family of proteins and may play a role in protein processing in limb, cardiac and reproductive system development. The mutations in BBS6 have been linked to Bardet-Biedl syndrome (BBS) which is a genetically heterogeneous, autosomal recessive disorder characterized by usually severe pigmentary retinopathy, early onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. It may also get involved in cellular organization processes, in particular relating to ciliary/flagellar and centrosomal activities.