BCAM Rekombinanter Antikörper

BCAM Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

250778C11

Kat-Nr. : 98521-3-PBS

Synonyme

Auberger B antigen, Basal cell adhesion molecule, B-CAM cell surface glycoprotein, CD239, F8/G253 antigen

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  FC experiment of Human peripheral blood erythrocytes using 98521-3-RR (same clone as 98521-3-PBS)

  1x10^6 human peripheral blood erythrocytes were surface stained with 0.25 ug Anti-Human BCAM Rabbit RecAb (98521-3-RR, Clone: 250778C11) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98521-3-PBS in a different storage buffer formulation.

• 

  FC experiment of Human peripheral blood erythrocytes using 98521-3-RR (same clone as 98521-3-PBS)

  1x10^6 human peripheral blood erythrocytes were surface stained with 0.25 ug Anti-Human BCAM Rabbit RecAb (98521-3-RR, Clone: 250778C11) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98521-3-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98521-3-PBS bindet in FC BCAM und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: BCAM fusion protein Eg2567
• Vollständiger Name: basal cell adhesion molecule (Lutheran blood group)
• Berechnetes Molekulargewicht: 67 kDa
• GenBank-Zugangsnummer: BC050450
• Gene symbol: BCAM
• Gene ID (NCBI): 4059
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

Basal cell adhesion molecule (Lu/BCAM) is a membrane-bound glycoprotein of the immunoglobulin superfamily (IgSF), functioning as a receptor for the extracellular matrix protein, laminin. BCAM (Lutheran/basal cell-adhesion molecule, a glycoprotein) belongs to the immunoglobulin superfamily which contains both Lu blood group and BCAM tumor-associated antigens. Proteomics analysis suggests that BCAM might be a potential biomarker for pancreatic cancer (PMID: 19199705). BCAM, involved in cell adhesion and migration, can also promote tumor metastasis and has been elucidated to play a functional role in the metastasis of thyroid cancer and gastric cancer (PMID: 10728810, 35941663).