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BCL2 Monoklonaler Antikörper

BCL2 Monoklonal Antikörper für IHC, IF/ICC, IF-P, IP, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human

Anwendung

IHC, IF/ICC, IF-P, IP, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4H8C6

Kat-Nr. : 60178-1-PBS

Synonyme

BCL-2, 4H8C6



Geprüfte Anwendungen

Produktinformation

60178-1-PBS bindet in IHC, IF/ICC, IF-P, IP, Cytometric bead array, Indirect ELISA BCL2 und zeigt Reaktivität mit Hausschwein, human

Getestete Reaktivität Hausschwein, human
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen BCL2 fusion protein Ag3508
Vollständiger Name B-cell CLL/lymphoma 2
Berechnetes Molekulargewicht 26 kDa
Beobachtetes Molekulargewicht 26 kDa
GenBank-ZugangsnummerBC027258
Gene symbol BCL2
Gene ID (NCBI) 596
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

1) What is Bcl-2?
Bcl-2 (B-cell lymphoma 2) is an outer mitochondrial membrane protein that via heterodimerization with BAX proteins controls apoptosis. Abnormalities of Bcl-2 activity can lead to cancer, autoimmune diseases, and schizophrenia.
2) FAQs for Bcl-2

A) How to measure Bcl-2 and Bax apoptotic markers by western blotting
Generally, Bcl-2 protein is considered to have anti-apoptotic activity, while Bax has apoptotic activity. Comparing the ratio between Bcl-2 and Bax protein levels in different samples or cells subjected to treatments can reflect the apoptotic state of the cells. Expression of Bax can vary between cell lines and it is important to compare it to Bcl-2 levels.
B) What band size should I expect in western blotting for Bcl-2?
The molecular weight of Bcl-2 is 26 kDa.