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BCL2L13 Rekombinanter Antikörper

BCL2L13 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250705F1

Kat-Nr. : 86183-1-PBS

Synonyme

Bcl2-L-13, Bcl-2-like protein 13, Bcl-rambo, CD003, MIL 1

Filter:
  • Western Blot (WB) analysis of various lysates using BCL2L13 Recombinant antibody (86183-1-RR)

    WB analysis using 86183-1-RR (same clone as 86183-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86183-1-RR (BCL2L13 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86183-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86183-1-RR

    Affinity and Kinetic Characterization of 86183-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86183-1-RR against Human BCL2L13 were performed. The affinity constant is 1.32 nM.

Geprüfte Anwendungen

Produktinformation

86183-1-PBS bindet in WB, Indirect ELISA BCL2L13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen BCL2L13 fusion protein Ag9841
Vollständiger Name BCL2-like 13 (apoptosis facilitator)
Berechnetes Molekulargewicht 485 aa, 53 kDa
Beobachtetes Molekulargewicht 85 kDa
GenBank-ZugangsnummerBC003032
Gene symbol BCL2L13
Gene ID (NCBI) 23786
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BCL2L13/MIL1 gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. BLC2L13 gene is highest expressed in heart, placenta and pancreas. The encoded protein Bcl-rambo may promote the activation of caspase-3 and apoptosis. The Bcl-rambo cell death activity was induced by its membrane-anchored C-terminal domain and not by the Bcl-2 homology region (PMID: 11262395). Multivariate analysis demonstrated that high expression of BCL2L13 was an independent prognostic factor for in childhood acute lymphoblastic leukemia (PMID: 20109966).