BDNF Monoklonaler Antikörper

BDNF Monoklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1E5C5

Kat-Nr. : 66292-1-PBS

Synonyme

Brain-derived neurotrophic factor, brain derived neurotrophic factor, BDNF precursor form, 1E5C5



Geprüfte Anwendungen

Produktinformation

66292-1-PBS bindet in WB, IF/ICC, Indirect ELISA BDNF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen BDNF fusion protein Ag11329
Vollständiger Name brain-derived neurotrophic factor
Berechnetes Molekulargewicht 247 aa, 28 kDa
Beobachtetes Molekulargewicht 32 kDa
GenBank-ZugangsnummerBC029795
Gene symbol BDNF
Gene ID (NCBI) 627
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

1) What is BDNF?

BDNF (brain-derived neurotrophic factor) is a small secreted growth factor that is important for the development and plasticity of the central nervous system and vital for long-term memory. Selected polymorphisms of BDNF have been shown to increase susceptibility to memory impairment and selected eating and mental disorders.

2) FAQs for BDNF

A) I can detect more than one band in my samples
BDNF is a neurotrophin that is a subject of maturation by proteolytic cleavage. The precursor protein (pre-proBDNF) is first cleaved to proBDNF (~34 kDa) by removing a signal peptide, and then to a mature form of BDNF (14 kDa). Additionally, (pre-)proBDNF can form dimers that run between 50 and 60 kDa, and a minor truncated form of proBDNF running at 28 kDa has also been reported (PMID: 11152678).