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BEX1/2 Polyklonaler Antikörper

BEX1/2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12390-1-PBS

Synonyme

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  • Western Blot (WB) analysis of human brain tissue using BEX1/2 Polyclonal antibody (12390-1-AP)

    WB analysis of human brain using 12390-1-AP (same clone as 12390-1-PBS)

    human brain tissue were subjected to SDS PAGE followed by western blot with 12390-1-AP (BEX1/2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human medulloblastoma tissue using BEX1/2 Polyclonal antibody (12390-1-AP)

    IHC staining of human medulloblastoma using 12390-1-AP (same clone as 12390-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human medulloblastoma using 12390-1-AP (BEX1/2 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12390-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12390-1-PBS bindet in WB, IHC, Indirect ELISA BEX1/2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen BEX1/2 fusion protein Ag3066
Vollständiger Name brain expressed X-linked 2
Berechnetes Molekulargewicht 128 aa, 15 kDa
Beobachtetes Molekulargewicht 10-15 kDa
GenBank-ZugangsnummerBC015522
Gene symbol BEX2
Gene ID (NCBI) 84707
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BEX1 is a signaling adapter molecule involved in p75NTR/NGFR signaling. It lays a role in cell cycle progression and neuronal differentiation. BEX1 inhibits neuronal differentiation in response to nerve growth factor (NGF). BEX2 is a regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. It regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity. The homology between human BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2.