BICD2 Polyklonaler Antikörper
BICD2 Polyklonal Antikörper für WB, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
WB, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 29603-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
29603-1-PBS bindet in WB, Indirect ELISA BICD2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | BICD2 fusion protein Ag31279 |
| Vollständiger Name | bicaudal D homolog 2 (Drosophila) |
| Berechnetes Molekulargewicht | 855 aa, 97 kDa |
| Beobachtetes Molekulargewicht | 93-96 kDa |
| GenBank-Zugangsnummer | BC073970 |
| Gene symbol | BICD2 |
| Gene ID (NCBI) | 23299 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Protein bicaudal D homolog 2 (BICD2) acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form. Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:25962623).

