BIK Monoklonaler Antikörper

BIK Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

1B1C10

Kat-Nr. : 68438-1-PBS

Synonyme

Apoptosis inducer NBK, BIK, BIP1, BP4, NBK

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  WB analysis using 68438-1-Ig (same clone as 68438-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68438-1-Ig (BIK antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68438-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68438-1-PBS bindet in WB, ELISA BIK und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: BIK fusion protein Ag6353
• Vollständiger Name: BCL2-interacting killer (apoptosis-inducing)
• Berechnetes Molekulargewicht: 18 kDa
• Beobachtetes Molekulargewicht: 20 kDa
• GenBank-Zugangsnummer: BC001599
• Gene symbol: BIK
• Gene ID (NCBI): 638
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.