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BMF Polyklonaler Antikörper

BMF Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 18298-1-PBS

Synonyme

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  • Immunoprecipitation (IP) experiment of HEK-293 cells using BMF Polyclonal antibody (18298-1-AP)

    IP experiment of HEK-293 using 18298-1-AP (same clone as 18298-1-PBS)

    IP result of anti-BMF (IP:18298-1-AP, 4ug; Detection:18298-1-AP 1:1000) with HEK-293 cells lysate 1800 ug. This data was developed using the same antibody clone with 18298-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

18298-1-PBS bindet in IP, Indirect ELISA BMF und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name Bcl2 modifying factor
Berechnetes Molekulargewicht 21 kDa
Beobachtetes Molekulargewicht 24 kDa
GenBank-ZugangsnummerBC069505
Gene symbol BMF
Gene ID (NCBI) 90427
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BMF belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities such as central regulators of apoptotic cell death. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. BMF is widely expressed in tissues such as pancreas, liver and kidney, and in hematopoietic tissues.