BMP9 Polyklonaler Antikörper

BMP9 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33159-1-AP

Synonyme

BMP-9, Bone morphogenetic protein 9, Gdf2, GDF-2, Growth/differentiation factor 2

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  WB analysis using 33159-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33159-1-AP (BMP9 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Mauslebergewebe, Rattenlebergewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:6000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

33159-1-AP bindet in WB, ELISA BMP9 und zeigt Reaktivität mit Maus, Ratten

• Getestete Reaktivität: Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BMP9 fusion protein Eg2482
• Vollständiger Name: growth differentiation factor 2
• Berechnetes Molekulargewicht: 48 kDa
• Beobachtetes Molekulargewicht: 33 kDa
• GenBank-Zugangsnummer: NM_019506.4
• Gene symbol: BMP9
• Gene ID (NCBI): 12165
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Bone Morphogenetic Protein 9 (BMP9), also known as Growth Differentiation Factor 2 (GDF-2), is a cytokine belonging to the transforming growth factor-β (TGF-β) superfamily. BMP9 is mainly produced by hepatocytes and hepatic stellate cells in the liver and is secreted into the bloodstream, where it acts as a circulating factor involved in various physiological processes. BMP9 is synthesized as a precursor protein (pre-proBMP9) composed of 429 amino acids (aa) that includes a 22 aa signal peptide, a 297 aa prodomain (33 kDa) and a 110 aa mature protein (12.5 kDa). It is then cleaved by serine endoproteases, leading to a short dimeric mature form of 25 kDa, and the prodomain which can remain noncovalently associated with the mature short form, giving a size of about 100 kDa. (PMID:21710321)