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BMPR1B Polyklonaler Antikörper

BMPR1B Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26696-1-PBS

Synonyme

BMP type 1B receptor, BMP type-1B receptor, BMPR 1B, BMPR-1B, Bone morphogenetic protein receptor type-1B

Filter:
  • Western Blot (WB) analysis of various lysates using BMPR1B Polyclonal antibody (26696-1-AP)

    WB analysis using 26696-1-AP (same clone as 26696-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26696-1-AP (BMPR1B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat ovary tissue using BMPR1B Polyclonal antibody (26696-1-AP)

    IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat ovary tissue using BMPR1B Polyclonal antibody (26696-1-AP)

    IHC staining of rat ovary using 26696-1-AP (same clone as 26696-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat ovary tissue slide using 26696-1-AP (BMPR1B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of MCF-7 cells using BMPR1B Polyclonal antibody (26696-1-AP)

    IF Staining of MCF-7 using 26696-1-AP (same clone as 26696-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using BMPR1B antibody (26696-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26696-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26696-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA BMPR1B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen BMPR1B fusion protein Ag24902
Vollständiger Name bone morphogenetic protein receptor, type IB
Berechnetes Molekulargewicht 57 kDa
Beobachtetes Molekulargewicht 50 kDa
GenBank-ZugangsnummerBC047773
Gene symbol BMPR1B
Gene ID (NCBI) 658
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BMPR1B (Bone morphogenetic protein receptor type-1B) is also named as CDw293. BMPR1B belongs to the protein kinase superfamily. BMPR1B is on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. BMPR1B is receptor for BMP7/OP-1 and GDF5. BMPR1B Positively regulates chondrocyte differentiation through GDF5 interaction.