BNP Polyklonaler Antikörper

BNP Polyklonal Antikörper für IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13299-1-PBS

Synonyme

Natriuretic peptides B, NPPB, BNP(3-29), BNP(2-31), BNP(1-30)

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  IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human heart using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human heart slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IHC staining of human brain using 13299-1-AP (same clone as 13299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human brain slide using 13299-1-AP (BNP Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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  IF Staining of HepG2 using 13299-1-AP (same clone as 13299-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using BNP antibody (13299-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 13299-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13299-1-PBS bindet in IHC, IF/ICC, Indirect ELISA BNP und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BNP fusion protein Ag4039
• Vollständiger Name: natriuretic peptide precursor B
• Berechnetes Molekulargewicht: 134 aa, 15 kDa
• GenBank-Zugangsnummer: BC025785
• Gene symbol: BNP
• Gene ID (NCBI): 4879
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.