BRD7 Polyklonaler Antikörper

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BRD7 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 51009-2-PBS

Synonyme

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  WB analysis of HeLa using 51009-2-AP (same clone as 51009-2-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis using 51009-2-AP (same clone as 51009-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis of rat brain using 51009-2-AP (same clone as 51009-2-PBS)

  rat brain tissue were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis of L02 using 51009-2-AP (same clone as 51009-2-PBS)

  L02 cells were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse cerebellum using 51009-2-AP (same clone as 51009-2-PBS)

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse lung using 51009-2-AP (same clone as 51009-2-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  WB analysis of SH-SY5Y using 51009-2-AP (same clone as 51009-2-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 51009-2-AP (BRD7 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human colon cancer using 51009-2-AP (same clone as 51009-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 51009-2-AP (BRD7 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 51009-2-AP (BRD7 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

• 

  IHC staining of human cervical cancer using 51009-2-AP (same clone as 51009-2-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 51009-2-AP (BRD7 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 51009-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

51009-2-PBS bindet in WB, IHC, Indirect ELISA BRD7 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BRD7 fusion protein Ag3911
• Vollständiger Name: bromodomain containing 7
• Berechnetes Molekulargewicht: 651 aa, 74 kDa
• Beobachtetes Molekulargewicht: 70-74 kDa
• GenBank-Zugangsnummer: BC050728
• Gene symbol: BRD7
• Gene ID (NCBI): 29117
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.