BRD7 Rekombinanter Antikörper

BRD7 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250776B2

Kat-Nr. : 86176-2-PBS

Synonyme

BP75, Bromodomain-containing protein 7, CELTIX1, NAG4, Protein CELTIX 1

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  WB analysis using 86176-2-RR (same clone as 86176-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86176-2-RR (BRD7 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86176-2-PBS in a different storage buffer formulation.

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  WB analysis of PC-3 using 86176-2-RR (same clone as 86176-2-PBS)

  PC-3 cells were subjected to SDS PAGE followed by western blot with 86176-2-RR (BRD7 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86176-2-PBS in a different storage buffer formulation.

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  WB analysis of mouse lung using 86176-2-RR (same clone as 86176-2-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 86176-2-RR (BRD7 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86176-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

86176-2-PBS bindet in WB, Indirect ELISA BRD7 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: BRD7 fusion protein Ag1461
• Vollständiger Name: bromodomain containing 7
• Berechnetes Molekulargewicht: 651 aa, 74 kDa
• Beobachtetes Molekulargewicht: 74-78 kDa
• GenBank-Zugangsnummer: BC050728
• Gene symbol: BRD7
• Gene ID (NCBI): 29117
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BRD7 (bromodomain containing 7), is a subunit of poly-bromo-associated BRG1-associated factor (PBAF)-specific Swi/Snf chromatin remodeling complexes.BRD7 is proposed as a tumor suppressor protein, since its identification as an important component of both functional p53 and BRCA1 (breast cancer 1, early onset) pathways. BRD7 could down-regulate the GSK3beta phosphotransferase activity as dephosphorylation of GSK3B at 'Tyr-216', thus activate the Wnt signaling pathway in a DVL1-dependent manner.