BTG1 Polyklonaler Antikörper

BTG1 Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14879-1-PBS

Synonyme

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  IHC staining of human thyroid cancer using 14879-1-AP

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 14879-1-AP (BTG1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human thyroid cancer using 14879-1-AP

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 14879-1-AP (BTG1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human lymphoma using 14879-1-AP (same clone as 14879-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 14879-1-AP (BTG1 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 14879-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lymphoma using 14879-1-AP (same clone as 14879-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lymphoma using 14879-1-AP (BTG1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 14879-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14879-1-PBS bindet in IHC, ELISA BTG1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: BTG1 fusion protein Ag6651
• Vollständiger Name: B-cell translocation gene 1, anti-proliferative
• Berechnetes Molekulargewicht: 19 kDa
• GenBank-Zugangsnummer: BC064953
• Gene symbol: BTG1
• Gene ID (NCBI): 694
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BTG1 is a member of the TOB/BTG family of proteins known to inhibit cell proliferation and negatively regulate the cell cycle (PMID: 25017022). It is strongly expressed in quiescent cells (maximal in the G0/G1 phase) and down-regulated as the cells enter the growth cycle (PMID: 1373383). BTG1 protein is localized in cytoplasm and nucleus, and can interact with CAF1 and PRMT1 (PMID: 1113675, 9712883, 26622543). The aberration of BTG1 expression is associated with B-cell lymphocytic leukemia, and may serve as a diagnostic indicator and prognostic marker of thyroid carcinoma (PMID: 2069907, 25017022).