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BXDC5 Polyklonaler Antikörper

BXDC5 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33133-1-PBS

Synonyme

Brix domain-containing protein 5, Ribosome biogenesis protein RPF1, Ribosome production factor 1, Ribosome Production Factor 1 Homolog, RPF1

Filter:
  • Western Blot (WB) analysis of various lysates using BXDC5 Polyclonal antibody (33133-1-AP)

    WB analysis using 33133-1-AP (same clone as 33133-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33133-1-AP (BXDC5 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33133-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using BXDC5 Polyclonal antibody (33133-1-AP)

    IF Staining of U2OS using 33133-1-AP (same clone as 33133-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using BXDC5 antibody (33133-1-AP) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 33133-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33133-1-PBS bindet in WB, IF/ICC, Indirect ELISA BXDC5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen BXDC5 fusion protein Ag37505
Vollständiger Name brix domain containing 5
Berechnetes Molekulargewicht 349 aa, 40 kDa
Beobachtetes Molekulargewicht48 kDa
GenBank-ZugangsnummerBC016051
Gene symbol BXDC5
Gene ID (NCBI) 80135
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BXDC5 (Brix domain-containing protein 5), also known as ribosome biogenesis protein RPF1, is a protein containing a Brix domain and is localized in the nucleolus. The Brix domain is a region that shares homology with the yeast protein Pitx1 (ribosome biogenesis protein BRX1). BXDC5 is a key factor in ribosome biogenesis, participating in the maturation of the 60S ribosomal subunit. This protein exerts its function by binding to specific rRNA structures and acts as a downstream effector molecule of the Ran signaling pathway, involved in ribosome biogenesis. In colorectal cancer (CRC), BXDC5 influences the occurrence and development of tumors by regulating ribosome biogenesis.