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BZRAP1 Polyklonaler Antikörper

BZRAP1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28241-1-PBS

Synonyme

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  • Western Blot (WB) analysis of Neuro-2a cells using BZRAP1 Polyclonal antibody (28241-1-AP)

    WB analysis of Neuro-2a using 28241-1-AP (same clone as 28241-1-PBS)

    Neuro-2a cells were subjected to SDS PAGE followed by western blot with 28241-1-AP (BZRAP1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28241-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28241-1-PBS bindet in WB, Indirect ELISA BZRAP1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen BZRAP1 fusion protein Ag28198
Vollständiger Name benzodiazapine receptor (peripheral) associated protein 1
Berechnetes Molekulargewicht 1857 aa, 200 kDa
Beobachtetes Molekulargewicht 200-235 kDa
GenBank-ZugangsnummerBC146852
Gene symbol BZRAP1
Gene ID (NCBI) 9256
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

BZRAP1, also named as TSPOAP1 and PBR-associated protein 1 (PRAX-1), is a cytoplasmic protein of 1857 residues. It plays a key role in inflammation, neuroinflammation, mental and metabolic diseases, and cancer. BZRAP1 predominantly expressed in the central nervous system, pituitary gland, and thymus, specially abundant in the CA1 subfield of the hippocampus. Tumor necrosis factor receptor 1 (TNFR1), vascular cell adhesion molecule 1 (VCAM1), cyclic AMP response element-binding protein 1 (CREB1), T-cell receptor (TCR), nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain containing 3 (NLRP3), DNA-dependent protein kinase (DNA-PK or PRKDC), and mitochondrial permeability transition pore (mPTP) were the major interaction partners of BZRAP1 (PMID: 34212002).