BCL2L1 Monoklonaler Antikörper
BCL2L1 Monoklonal Antikörper für WB, IHC, IF/ICC, FC (Intra), Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IHC, IF/ICC, FC (Intra), Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
4C12A6
Kat-Nr. : 66020-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
66020-1-PBS bindet in WB, IHC, IF/ICC, FC (Intra), Cytometric bead array, Indirect ELISA BCL2L1 und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte | 
| Wirt / Isotyp | Maus / IgG2b | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | BCL2L1 fusion protein Ag18037 | 
| Vollständiger Name | BCL2-like 1 | 
| Berechnetes Molekulargewicht | 26 kDa | 
| Beobachtetes Molekulargewicht | 30 kDa | 
| GenBank-Zugangsnummer | BC019307 | 
| Gene symbol | BCL2L1 | 
| Gene ID (NCBI) | 598 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-A-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
BCL2L1 is a member of the BCL-2 protein family. BCL2L1 is expressed as three isoforms, Bcl-X(L),Bcl-X(s) and Bcl-X(beta), and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein, acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX, BAK or BCL2, and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188), acting as an apoptotic activator.































