Beta-2-Microglobulin Rekombinanter Antikörper

Beta-2-Microglobulin Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

241308D5

Kat-Nr. : 98165-1-RR

Synonyme

B2M, 241308D5, HDCMA22P, CDABP0092, Beta-2-microglobulin form pI 5.3

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  FC experiment of human peripheral blood leukocytes using 98165-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human B2M Rabbit Recombinant Antibody (98165-1-RR, Clone:241308D5) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

• 

  Affinity and Kinetic Characterization of 98165-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98165-1-RR against Human Beta-2-Microglobulin were performed. The affinity constant is 0.743 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98165-1-RR bindet in FC Beta-2-Microglobulin und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Fusionsprotein
• Vollständiger Name: beta-2-microglobulin
• Berechnetes Molekulargewicht: 119 aa, 14 kDa
• GenBank-Zugangsnummer: BC032589
• Gene symbol: B2M
• Gene ID (NCBI): 567
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

Beta-2-microglobulin (B2M) is a component of MHC class I molecules, which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions due to shedding from cell surfaces or intracellular release. B2M has various biological functions, including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases.