C10orf88 Polyklonaler Antikörper

C10orf88 Polyklonal Antikörper für IHC, IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

IHC, IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26026-1-PBS

Synonyme

ATPase PAAT, EC:3.6.1.-, PAAT, Protein associated with ABC transporters

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  IP experiment of SH-SY5Y using 26026-1-AP (same clone as 26026-1-PBS)

  IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with SH-SY5Y cells lysate 1920 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IP experiment of HEK-293 using 26026-1-AP (same clone as 26026-1-PBS)

  IP result of anti-C10orf88 (IP:26026-1-AP, 4ug; Detection:26026-1-AP 1:600) with HEK-293 cells lysate 1600 ug. This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IHC staining of rat pancreas using 26026-1-AP (same clone as 26026-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat pancreas tissue slide using 26026-1-AP (C10orf88 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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  IF Staining of A549 using 26026-1-AP (same clone as 26026-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed A549 cells using C10orf88 antibody (26026-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 26026-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

26026-1-PBS bindet in IHC, IF/ICC, IP, Indirect ELISA C10orf88 und zeigt Reaktivität mit human, Ratten

• Getestete Reaktivität: human, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: C10orf88 fusion protein Ag22971
• Vollständiger Name: chromosome 10 open reading frame 88
• Berechnetes Molekulargewicht: 445 aa, 49 kDa
• Beobachtetes Molekulargewicht: 49 kDa
• GenBank-Zugangsnummer: BC032645
• Gene symbol: C10orf88
• Gene ID (NCBI): 80007
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C10orf88 (Chromosome 10 Open Reading Frame 88) is a mitochondria-localized protein that is thought to be associated with protein-binding activity of mitochondria and plays a role in mitochondrial dysfunction and metabolic diseases. Studies suggest that C10orf88 may be involved in cellular metabolism, cell cycle regulation, and maintenance of mitochondrial homeostasis. Its activity is closely related to ATP synthesis and oxidative phosphorylation in mitochondria, and may be affected by a variety of metabolic regulators (e.g., metformin, AICAR) and cell cycle regulators (e.g., rosavitine). In addition, inhibitors of C10orf88 (e.g., oryzanamycin, rotenone) modulate its activity by affecting ATP synthase and electron transport chain complex I in mitochondria.