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C13orf3 Polyklonaler Antikörper

C13orf3 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26320-1-PBS

Synonyme

RAMA1, SKA3, Spindle And Kinetochore Associated Complex Subunit 3, Spindle and kinetochore-associated protein 3

Filter:
  • Western Blot (WB) analysis of various lysates using C13orf3 Polyclonal antibody (26320-1-AP)

    WB analysis using 26320-1-AP (same clone as 26320-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26320-1-AP (C13orf3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26320-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26320-1-PBS bindet in WB, ELISA C13orf3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen C13orf3 fusion protein Ag23684
Vollständiger Name chromosome 13 open reading frame 3
Beobachtetes Molekulargewicht54 kDa
GenBank-ZugangsnummerBC048988
Gene symbol C13orf3
Gene ID (NCBI) 221150
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C13orf3 (now known as Ska3) is a component of a spindle- and mitophore-associated protein complex that regulates microtubule attachment to the mitophore during mitosis. Ska3 is localized to the outer side of the mitophore during mitosis and may be essential for normal chromosome segregation. In addition, deletion of Ska3 results in a delay in mid-mitotic division and an inability to silence the spindle checkpoint or enter prophase. Accumulation of Ska3 is dependent on Sgo1 proteins, whereas mitotic accumulation of Sgo1 in prophase is not dependent on Ska3. The discovery of Ska3 further refines the function of the Ska complex, which plays an important role in mitotic progression and chromosome segregation. The discovery of Ska3 in the prophase of Sgo1 is a key factor in mitosis and chromosome segregation.