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C16orf75 Polyklonaler Antikörper

C16orf75 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30529-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using C16orf75 Polyclonal antibody (30529-1-AP)

    WB analysis using 30529-1-AP (same clone as 30529-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30529-1-AP (C16orf75 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30529-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of U-251 cells using C16orf75 Polyclonal antibody (30529-1-AP)

    IF Staining of U-251 using 30529-1-AP (same clone as 30529-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U-251 cells using C16orf75 antibody (30529-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 30529-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30529-1-PBS bindet in WB, IF/ICC, Indirect ELISA C16orf75 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen C16orf75 fusion protein Ag32880
Vollständiger Name chromosome 16 open reading frame 75
Beobachtetes Molekulargewicht 19 kDa
GenBank-ZugangsnummerBC031016
Gene symbol C16orf75
Gene ID (NCBI) 116028
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C16orf75 is also named as BLM-associated protein of 18 kDa (BLAP18), RMI2, hRMI2 and RecQ-mediated genome instability protein 2. C16orf75 is essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. And RMI2 is essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM (PMID: 18923082, PMID: 18923083, PMID: 27977684).