C19orf63 Polyklonaler Antikörper

C19orf63 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30844-1-PBS

Synonyme

EMC10, ER Membrane Protein Complex Subunit 10, Hematopoietic signal peptide-containing membrane domain-containing protein 1, HSM1, HSS1

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  WB analysis using 30844-1-AP (same clone as 30844-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30844-1-AP (C19orf63 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 30844-1-AP (same clone as 30844-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 30844-1-AP (same clone as 30844-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 30844-1-AP (C19orf63 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30844-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

30844-1-PBS bindet in WB, IHC, Indirect ELISA C19orf63 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: C19orf63 fusion protein Ag34064
• Vollständiger Name: chromosome 19 open reading frame 63
• Beobachtetes Molekulargewicht: 28 kDa
• GenBank-Zugangsnummer: BC035001
• Gene symbol: C19orf63
• Gene ID (NCBI): 284361
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) is one of the key components of the highly conserved endoplasmic reticulum membrane protein complex (EMC). The core function of this complex is to act as an insertase and chaperone in the endoplasmic reticulum, assisting in the correct folding, assembly, and membrane integration of membrane proteins, and preventing the aggregation of misfolded proteins. Studies have shown that EMC10 plays a dual role in cells: within the cell, it ensures the biogenesis of important membrane proteins such as G protein-coupled receptors (GPCRs); moreover, it can be secreted outside the cell (referred to as sEMC10), where it acts as a novel signaling molecule to activate the hypothalamic-pituitary axis, regulating energy metabolism and body weight in the body, and is closely related to obesity and metabolic diseases.