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C1r Polyklonaler Antikörper

C1r Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17346-1-PBS

Synonyme

Complement C1r, Complement C1r subcomponent, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, EC:3.4.21.41

Filter:
  • Western Blot (WB) analysis of various lysates using C1r Polyclonal antibody (17346-1-AP)

    WB analysis using 17346-1-AP (same clone as 17346-1-PBS)

    human plasma was subjected to SDS PAGE followed by western blot with 17346-1-AP (C1r antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human blood using C1r Polyclonal antibody (17346-1-AP)

    WB analysis of human blood using 17346-1-AP (same clone as 17346-1-PBS)

    Human blood was subjected to SDS PAGE, followed by western blot with 17346-1-AP (C1r Antibody) at a dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using C1r Polyclonal antibody (17346-1-AP)

    IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17346-1-AP (C1r Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human liver tissue using C1r Polyclonal antibody (17346-1-AP)

    IHC staining of human liver using 17346-1-AP (same clone as 17346-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 17346-1-AP (C1R Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 17346-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17346-1-PBS bindet in WB, IHC, Indirect ELISA C1r und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen C1r fusion protein Ag11390
Vollständiger Name complement component 1, r subcomponent
Berechnetes Molekulargewicht 705 aa, 80 kDa
Beobachtetes Molekulargewicht 85 kDa, 30 kDa
GenBank-ZugangsnummerBC035220
Gene symbol C1R
Gene ID (NCBI) 715
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein that can be cleaved into an A chain and a B chain upon activation. This antibody recognizes the full-length C1r chain and the cleaved B chain.