C1S Polyklonaler Antikörper

C1S Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14554-1-PBS

Synonyme

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  WB analysis of human plasma using 14554-1-AP (same clone as 14554-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 14554-1-AP (same clone as 14554-1-PBS)

  rat plasma lysates were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human plasma using 14554-1-AP (same clone as 14554-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 14554-1-AP (C1S antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 14554-1-AP (same clone as 14554-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 14554-1-AP (C1S antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14554-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

14554-1-PBS bindet in WB, IHC, Indirect ELISA C1S und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: C1S fusion protein Ag5977
• Vollständiger Name: complement component 1, s subcomponent
• Berechnetes Molekulargewicht: 77 kDa
• Beobachtetes Molekulargewicht: 88 kDa
• GenBank-Zugangsnummer: BC056903
• Gene symbol: C1S
• Gene ID (NCBI): 716
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r activates C1s so that it can, in turn, activate C2 and C4. C1s is a glycoprotein of approximately 88 kDa, which is activated by cleavage into an A chain and a B chain.