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C1r Rekombinanter Antikörper

C1r Rekombinant Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242596F5

Kat-Nr. : 85029-4-PBS

Synonyme

242596F5, Complement C1r, Complement C1r subcomponent, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain

Filter:
  • Western Blot (WB) analysis of human plasma using C1r Recombinant antibody (85029-4-RR)

    WB analysis of human plasma using 85029-4-RR (same clone as 85029-4-PBS)

    human plasma was subjected to SDS PAGE followed by western blot with 85029-4-RR (C1R antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85029-4-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using C1r Recombinant antibody (85029-4-RR)

    IHC staining of mouse liver using 85029-4-RR (same clone as 85029-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85029-4-RR (C1r antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85029-4-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using C1r Recombinant antibody (85029-4-RR)

    IHC staining of mouse liver using 85029-4-RR (same clone as 85029-4-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85029-4-RR (C1r antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85029-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85029-4-RR

    Affinity and Kinetic Characterization of 85029-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85029-4-RR against Human C1r were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

85029-4-PBS bindet in WB, IHC, Indirect ELISA C1r und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen C1r fusion protein Ag11390
Vollständiger Name complement component 1, r subcomponent
Berechnetes Molekulargewicht 705 aa, 80 kDa
Beobachtetes Molekulargewicht85 kDa
GenBank-ZugangsnummerBC035220
Gene symbol C1R
Gene ID (NCBI) 715
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The first component of complement is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single-chain glycoprotein that can be cleaved into an A chain and a B chain upon activation.