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C4orf32 Polyklonaler Antikörper

C4orf32 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33453-1-PBS

Synonyme

FAM241A, Family With Sequence Similarity 241 Member A, Uncharacterized protein FAM241A

Filter:
  • Western Blot (WB) analysis of various lysates using C4orf32 Polyclonal antibody (33453-1-AP)

    WB analysis using 33453-1-AP (same clone as 33453-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33453-1-AP (C4orf32 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33453-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33453-1-PBS bindet in WB, Indirect ELISA C4orf32 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen C4orf32 fusion protein Ag38764
Vollständiger Name chromosome 4 open reading frame 32
Beobachtetes Molekulargewicht20 kDa
GenBank-ZugangsnummerBC022534
Gene symbol C4orf32
Gene ID (NCBI) 132720
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The FAM241A protein, also known as C4orf32, is a key regulatory factor that is localized to the Golgi apparatus. It plays an important role in maintaining the structural integrity of the Golgi apparatus and is involved in processes such as protein glycosylation and vesicle transport. More importantly, FAM241A has been identified as a novel negative regulator of the Hippo signaling pathway. It directly binds to and inhibits the activity of the core kinases MST1/2, thereby relieving the suppression of the downstream effectors YAP/TAZ, promoting cell proliferation, and inhibiting apoptosis. Aberrant function of FAM241A is closely related to the occurrence and development of various human diseases, especially tumors, making it a highly promising target for basic research and clinical translation.