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C5 Polyklonaler Antikörper

C5 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22492-1-PBS

Synonyme

C5, C5a, C5, C5b, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, Complement C5

Filter:
  • Western Blot (WB) analysis of various lysates using C5 Polyclonal antibody (22492-1-AP)

    WB analysis using 22492-1-AP (same clone as 22492-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22492-1-AP (C5 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22492-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using C5 Polyclonal antibody (22492-1-AP)

    WB analysis using 22492-1-AP (same clone as 22492-1-PBS)

    rat plasma was subjected to SDS PAGE followed by western blot with 22492-1-AP (C5 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22492-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22492-1-PBS bindet in WB, Indirect ELISA C5 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen C5 fusion protein Ag17882
Vollständiger Name complement component 5
Berechnetes Molekulargewicht 1676 aa, 188 kDa
Beobachtetes Molekulargewicht120 kDa, 70 kDa
GenBank-ZugangsnummerBC113740
Gene symbol C5
Gene ID (NCBI) 727
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The complement system is an important effector that bridges the innate and adaptive immune systems. The fifth component of complement, C5, is part of the complement cascade and plays an important role in inflammation and cell killing. It consists of disulfide-linked alpha and beta polypeptide chains but can be cleaved into two active peptides (C5a and C5b) by C5 convertases. Mutations and defects in C5 are associated with severe recurrent infections. (PMID: 20010915; PMID: 8011297; PMID: 6554279)