C5AR1/CD88 Rekombinanter Antikörper

C5AR1/CD88 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

APC Fluorescent Dye

CloneNo.

241712D4

Kat-Nr. : APC-FcA98226

Synonyme

C5AR, C5AR1, C5A, C5a anaphylatoxin chemotactic receptor 1, C5a R

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  FC experiment of human peripheral blood leukocytes using APC-FcA98226

  1x10^6 human peripheral blood leukocytes were surface stained with FcZero-rAb™ PE Anti-Human CD16, and 5 ul APC Anti-Human C5AR1/CD88 Rabbit RecAb (APC-FcA98226, Clone: 241712D4) or APC Rabbit IgG Isotype Control RecAb (APC-FcA98136, Clone: 240953C9). Cells were not fixed.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: human peripheral blood leukocytes

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Produktinformation

APC-FcA98226 bindet in FC C5AR1/CD88 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: C5AR1/CD88 fusion protein Eg2185
• Vollständiger Name: complement component 5a receptor 1
• Berechnetes Molekulargewicht: 39kDa
• GenBank-Zugangsnummer: NM_001736.4
• Gene symbol: C5aR
• Gene ID (NCBI): 728
• Konjugation: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Hintergrundinformationen

C5aR, also named CD88, is a G protein-coupled receptor for the anaphylatoxin C5a, a cleavage product of the complement cascade. The C5a ligand is a proinflammatory component of host defense. C5aR is activated upon binding of the C5a molecule. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release, and superoxide anion production.