Complement C6 Polyklonaler Antikörper

Complement C6 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17239-1-PBS

Synonyme

C6, complement component 6, Complement component C6

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  WB analysis of human blood using 17239-1-AP (same clone as 17239-1-PBS)

  human blood were subjected to SDS PAGE followed by western blot with 17239-1-AP (C6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IP experiment of human plasma using 17239-1-AP (same clone as 17239-1-PBS)

  IP result of anti-Complement C6 (IP:17239-1-AP, 4ug; Detection:17239-1-AP 1:3000) with human plasma lysate 3200 ug. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 17239-1-AP (C6 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver cancer using 17239-1-AP (same clone as 17239-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 17239-1-AP (C6 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

17239-1-PBS bindet in WB, IHC, IP, Indirect ELISA Complement C6 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Complement C6 fusion protein Ag11083
• Vollständiger Name: complement component 6
• Berechnetes Molekulargewicht: 934 aa, 105 kDa
• Beobachtetes Molekulargewicht: 105-120 kDa
• GenBank-Zugangsnummer: BC035723
• Gene symbol: C6
• Gene ID (NCBI): 729
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.