C6orf130 Polyklonaler Antikörper

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• KD/KO Validated

C6orf130 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Rezensionen (1)

Kat-Nr. : 25249-1-AP

Synonyme

OARD1, [Protein ADP-ribosylglutamate] hydrolase OARD1, ADP-ribose glycohydrolase OARD1, EC:3.2.2.-, EC:3.5.1.-

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• 

  WB analysis of PC-3 using 25249-1-AP

  PC-3 cells were subjected to SDS PAGE followed by western blot with 25249-1-AP (C6orf130 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: PC-3-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:200-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 3 publications below

Produktinformation

25249-1-AP bindet in WB, ELISA C6orf130 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: C6orf130 fusion protein Ag19382
• Vollständiger Name: chromosome 6 open reading frame 130
• Berechnetes Molekulargewicht: 152 aa, 17 kDa
• Beobachtetes Molekulargewicht: 17 kDa
• GenBank-Zugangsnummer: BC011709
• Gene symbol: C6orf130
• Gene ID (NCBI): 221443
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

OARD1 (O-acetyl-ADP-ribose deacetylase 1), also known as TARG1 (Terminal ADP-ribose protein glycohydrolase 1) and C6orf130, is a ADP-ribose glycohydrolase that hydrolyzes ADP-ribose and acts on different substrates, such as proteins ADP-ribosylated on glutamate and O-acetyl-ADP-D-ribose (PMID: 21849506; 23474714; 23481255). The MW of this protein is 17 kDa, and this antibody specially recognises the 17 kDa protein.

Publikationen

Species	Application	Title
Human	WB	Nucleic Acids Res; TARG1 protects against toxic DNA ADP-ribosylation.; Authors - Callum Tromans-Coia
human	WB	Cell Rep; The interplay of TARG1 and PARG protects against genomic instability; Authors - Joséphine Groslambert ; KO Validated
human	WB	Mol Cell; PARP enzyme de novo synthesis of protein-free poly(ADP-ribose); Authors - Marie-France Langelier

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

Lisa (Verified Customer) (09-17-2025)

Generally a good working antibody, but not outstanding

• Applications: Western Blot
• Primary Antibody Dilution: 1:1000