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G6B Polyklonaler Antikörper

G6B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 26131-1-PBS

Synonyme

C6orf25, G6B-B, Megakaryocyte and platelet inhibitory receptor G6b, MPIG6B, NG31

Filter:
  • Western Blot (WB) analysis of various lysates using G6B Polyclonal antibody (26131-1-AP)

    WB analysis using 26131-1-AP (same clone as 26131-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 26131-1-AP (C6orf25 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26131-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

26131-1-PBS bindet in WB, Indirect ELISA G6B und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen G6B fusion protein Ag23442
Vollständiger Name chromosome 6 open reading frame 25
Beobachtetes Molekulargewicht 24-29 kDa
GenBank-ZugangsnummerBC113719
Gene symbol C6orf25
Gene ID (NCBI) 80739
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

C6orf25, also called G6B, is an inhibitory receptor expressed on the surface of platelets,and it acts as a critical regulator of hematopoietic lineage differentiation, megakaryocyte function and platelet production (PMID: 17311996; 12665801; 27743390). C6orf25 has seven isoforms. Isoform B is the only isoform to contain both a transmembrane region and 2 immunoreceptor tyrosine-based inhibitor motifs (ITIMs) and, thus, the only one which probably has a role of inhibitory receptor. Isoform A may be the activating counterpart of isoform B (PMID: 11544253).