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C8G Rekombinanter Antikörper

C8G Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242479G11

Kat-Nr. : 85652-1-PBS

Synonyme

C8C

Filter:
  • Western Blot (WB) analysis of various lysates using C8G Recombinant antibody (85652-1-RR)

    WB analysis using 85652-1-RR (same clone as 85652-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of human plasma using C8G Recombinant antibody (85652-1-RR)

    WB analysis of human plasma using 85652-1-RR (same clone as 85652-1-PBS)

    human plasma were subjected to SDS PAGE followed by western blot with 85652-1-RR (C8G antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85652-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85652-1-PBS bindet in WB, Indirect ELISA C8G und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen C8G fusion protein Ag18261
Vollständiger Name complement component 8, gamma polypeptide
Berechnetes Molekulargewicht 202 aa, 22 kDa
Beobachtetes Molekulargewicht18-22 kDa
GenBank-ZugangsnummerBC113626
Gene symbol C8G
Gene ID (NCBI) 733
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The gamma chain of complement component 8 (C8G) is one of three different subunits (alpha, beta, and gamma) of the eighth complement component (C8), which is a component of the MAC (membrane attack complex) (PMID:33382892). Although the roles of C8A and C8B are directly associated with MAC formation, C8G is not essential in the assembly and activity of the MAC (PMID:11960635). Moreover, C8G was shown to inhibit neuroinflammation by interfering with the sphingosine-1-phosphate (S1P)-S1PR2 interaction (PMID:34149451).