C9orf114 Polyklonaler Antikörper

C9orf114 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33571-1-PBS

Synonyme

CENP-32, Centromere protein 32, EC:2.1.1.-, Kinetochore-associated protein, Putative methyltransferase C9orf114

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  WB analysis using 33571-1-AP (same clone as 33571-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33571-1-AP (C9orf114 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33571-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

33571-1-PBS bindet in WB, Indirect ELISA C9orf114 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: C9orf114 fusion protein Ag38014
• Vollständiger Name: chromosome 9 open reading frame 114
• Beobachtetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: BC063644
• Gene symbol: C9orf114
• Gene ID (NCBI): 51490
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPOUT1 (SPOUT domain-containing methyltransferase 1), also known as CENP32 or C9orf114, is a methyltransferase containing a SPOUT domain. This protein is highly expressed in the nucleolus and is crucial for ribosome function. SPOUT1 has been identified as an essential protein for cell survival in both Drosophila and humans. Moreover, mutations in SPOUT1 are associated with developmental epileptic encephalopathy (DEE) in humans, characterized by infantile seizures and intellectual disability.