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CA2 Rekombinanter Antikörper

CA2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242559B4

Kat-Nr. : 84954-4-PBS

Synonyme

Car2, CA-II, CAII, CAC, CA II

Filter:
  • Western Blot (WB) analysis of various lysates using CA2 Recombinant antibody (84954-4-RR)

    WB analysis using 84954-4-RR (same clone as 84954-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84954-4-RR (CA2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84954-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84954-4-RR

    Affinity and Kinetic Characterization of 84954-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84954-4-RR against Human CA2 were performed. The affinity constant is 23.5 nM.

Geprüfte Anwendungen

Produktinformation

84954-4-PBS bindet in WB, Indirect ELISA CA2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CA2 fusion protein Ag10680
Vollständiger Name carbonic anhydrase II
Berechnetes Molekulargewicht 260 aa, 29 kDa
Beobachtetes Molekulargewicht29 kDa
GenBank-ZugangsnummerBC011949
Gene symbol CA2
Gene ID (NCBI) 760
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CA2(carbonic anhydrase II ) is also called Car2, CA-II, and CAII and belongs to the alpha-carbonic anhydrase family. It reversibly hydrates CO2 in cellular ion transport and homeostasis. CA2 is essential for bone resorption and osteoclast differentiation. It regulates SLC9A1 activity via a phosphorylation-regulated CAII binding site in SLC9A1 tail(PMID:16475831). It also may be involved in brain development (PMID:16825953). Defects in CA2 cause osteopetrosis autosomal recessive type 3 (OPTB3).