CACNA1H Polyklonaler Antikörper

CACNA1H Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28092-1-PBS

Synonyme

CACNA1HB, Cav3.2, EIG6, FLJ90484, Low-voltage-activated calcium channel alpha1 3.2 subunit

---

• 

  WB analysis using 28092-1-AP (same clone as 28092-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28092-1-AP (CACNA1H antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28092-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

28092-1-PBS bindet in WB, Indirect ELISA CACNA1H und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: CACNA1H fusion protein Ag26094
• Vollständiger Name: calcium channel, voltage-dependent, T type, alpha 1H subunit
• Berechnetes Molekulargewicht: 259 kDa
• Beobachtetes Molekulargewicht: 259 kDa
• GenBank-Zugangsnummer: NM_001005407
• Gene symbol: CACNA1H
• Gene ID (NCBI): 8912
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Voltage-dependent T-type calcium channel subunit alpha-1H (CACNA1H) is located in the plasma membrane of various tissues, including the brain cortex, amygdala, caudate nucleus, putamen, kidney, liver, and heart. This subunit regulates muscle contraction, secretion, neurotransmission, and gene expression by forming the pore (PMID: 33985586). Predominantly, the changes observed are missense mutations associated with gain-of-function, resulting in an increased influx of calcium into adrenal cells (PMID: 33985586; 37311830).