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CACNA2D2 Polyklonaler Antikörper

CACNA2D2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22145-1-PBS

Synonyme

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  • Western Blot (WB) analysis of SH-SY5Y cells using CACNA2D2 Polyclonal antibody (22145-1-AP)

    WB analysis of SH-SY5Y using 22145-1-AP (same clone as 22145-1-PBS)

    WB result of CACNA2D2 antibody (22145-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CACNA2D2 transfected SH-SY5Y cells. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using CACNA2D2 Polyclonal antibody (22145-1-AP)

    WB analysis using 22145-1-AP (same clone as 22145-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22145-1-AP (CACNA2D2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22145-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22145-1-PBS bindet in WB, Indirect ELISA CACNA2D2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CACNA2D2 fusion protein Ag17580
Vollständiger Name calcium channel, voltage-dependent, alpha 2/delta subunit 2
Berechnetes Molekulargewicht 1145 aa, 129 kDa
Beobachtetes Molekulargewicht100-112 kDa
GenBank-ZugangsnummerBC152438
Gene symbol CACNA2D2
Gene ID (NCBI) 9254
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CACNA2D2 (calcium voltage-gated channel auxiliary subunit alpha2delta 2), also known as CASVDD. It is expected to be located in cell membrane. The protein is predominantly present in cerebellar cortex. Present in various lung tumor cell lines, while it is absent in normal lung (at protein level). Highly expressed in heart, lung, testis, pancreas and skeletal muscle. Also expressed in kidney, liver, placenta and brain (PMID: 10766861). The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel (PMID: 15111129). The molecular weight of CACNA2D2 is 129 kDa, and it can recognize other isoforms, which can be cut into fragments.