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CACTIN Polyklonaler Antikörper

CACTIN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32066-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CACTIN Polyclonal antibody (32066-1-AP)

    WB analysis using 32066-1-AP (same clone as 32066-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32066-1-AP (CACTIN antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32066-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32066-1-PBS bindet in WB, Indirect ELISA CACTIN und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CACTIN fusion protein Ag35645
Vollständiger Name chromosome 19 open reading frame 29
Berechnetes Molekulargewicht 108 kDa, 89 kDa
Beobachtetes Molekulargewicht120 kDa
GenBank-ZugangsnummerNM_021231
Gene symbol C19orf29
Gene ID (NCBI) 58509
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CACTIN plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (PubMed:28062851).CACTIN was reported to be involved in the regulation of innate immune response (PubMed:20829348). CACTIN acts as a negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554). CACTIN contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (PubMed:20829348, PubMed:26363554). CACTIN has two isforms (89kDa and 108 kDa).