CALCA/Calcitonin Monoklonaler Antikörper

CALCA/Calcitonin Monoklonal Antikörper für WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, Cytometric bead array, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

1A12A1

Kat-Nr. : 68774-1-PBS

Synonyme

CALCA/CGRP, CALCA, Calcitonin, 1A12A1, CALC1

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  WB analysis of TT using 68774-1-Ig (same clone as 68774-1-PBS)

  TT cells were subjected to SDS PAGE followed by western blot with 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  Sample test of MP50293-1

  Cytometric bead array in cell lysate using MP50293-1, CALCA Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68774-1-PBS. Detection antibody: 68774-2-PBS. Cell lysate: TT, HepG2.

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  IHC staining of human thyroid cancer using 68774-1-Ig (same clone as 68774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human thyroid cancer using 68774-1-Ig (same clone as 68774-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 68774-1-Ig (CALCA/CGRP antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 68774-1-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP50293-1

  Cytometric bead array standard curve of MP50293-1, CALCA Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 68774-1-PBS. Detection antibody: 68774-2-PBS. Standard:Ag26141. Range: 0.781-100 ng/mL.

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Geprüfte Anwendungen

Produktinformation

68774-1-PBS bindet in WB, IHC, Cytometric bead array, Indirect ELISA, Sample test CALCA/Calcitonin und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: CALCA/Calcitonin fusion protein Ag26141
• Vollständiger Name: Calcitonin
• Berechnetes Molekulargewicht: 141 aa, 15 kDa
• Beobachtetes Molekulargewicht: 14 kDa
• GenBank-Zugangsnummer: BC093753
• Gene symbol: CALCA
• Gene ID (NCBI): 796
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Calcitonin is a peptide hormone consisting of 32 amino acids, primarily synthesized by the parafollicular cells (C cells) of the human thyroid gland. It plays a crucial role in regulating calcium levels in the blood by decreasing them. Calcitonin opposes the actions of parathyroid hormone, which increases blood calcium levels. Calcitonin works through a G protein-coupled receptor, known as the calcitonin receptor, which predominantly transmits signals via the cAMP and PLC/IP3 pathways. Its primary physiological effects are on osteoclasts and the tubular epithelium of kidneys.