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CAMK2B Rekombinanter Antikörper

CAMK2B Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251925D4

Kat-Nr. : 86858-1-PBS

Synonyme

Calcium/calmodulin-dependent protein kinase type II subunit beta, CaM kinase II subunit beta, CAM2, CaMK II subunit beta, CAMK2

Filter:
  • Western Blot (WB) analysis of U-251 cells using CAMK2B Recombinant monoclonal antibody (86858-1-RR)

    WB analysis of U-251 using 86858-1-RR (same clone as 86858-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86858-1-RR (CAMK2B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86858-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86858-1-PBS bindet in WB, Indirect ELISA CAMK2B und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen CAMK2B fusion protein Ag2119
Vollständiger Name calcium/calmodulin-dependent protein kinase II beta
Berechnetes Molekulargewicht 503 aa, 56 kDa
Beobachtetes Molekulargewicht50-70 kDa
GenBank-ZugangsnummerBC019070
Gene symbol CaMKII beta
Gene ID (NCBI) 816
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CAMK2B(Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named CAM2, CAMK2, and CAMKB, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. It is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. CAMK2B is a member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. It plays a distinct role in the induction of anergy in T lymphocytes, by differential regulation of IL10 and IL2 gene transcription suggesting MEF2A as a molecular target that can integrate different calcium signals(PMID:22578382). This protein has 8 isoforms produced by alternative splicing with a molecular weight between 50 kDa and 73 kDa. This antibody may have cross-reaction with CAMK2A/D/G due to the high homology.