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CAMK4 Monoklonaler Antikörper

CAMK4 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1G7A7

Kat-Nr. : 68452-1-PBS

Synonyme

CaM kinase GR, CaMK GR, CaMK IV, CAMK4

Filter:
  • Western Blot (WB) analysis of various lysates using CAMK4 Monoclonal antibody (68452-1-Ig)

    WB analysis using 68452-1-Ig (same clone as 68452-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68452-1-Ig (CAMK4 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68452-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68452-1-PBS bindet in WB, Indirect ELISA CAMK4 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen CAMK4 fusion protein Ag33332
Vollständiger Name calcium/calmodulin-dependent protein kinase IV
Berechnetes Molekulargewicht 473 aa, 52 kDa
Beobachtetes Molekulargewicht56-65 kDa
GenBank-ZugangsnummerBC025687
Gene symbol CAMK4
Gene ID (NCBI) 814
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CaMK4 (Calcium/calmodulin-dependent protein kinase IV) is a multifunctional serine/threonine kinase that regulates gene expression by activating transcription factors in a wide range of immune cells including T cells and antigen-presenting cells. The function of CaMK4 is suggested to be abnormal mainly in systemic lupus erythematosus (SLE), which is characterized by autoantibody production, immune complex formation, and immune dysregulation (PMID: 29252071). CaMKIV can translocate between the nucleus and cytoplasm (PMID: 21301225)