CAPG-Specific Polyklonaler Antikörper

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CAPG-Specific Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 19535-1-PBS

Synonyme

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  WB analysis of mouse lung using 19535-1-AP (same clone as 19535-1-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse kidney using 19535-1-AP (same clone as 19535-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  WB analysis of U-937 using 19535-1-AP (same clone as 19535-1-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  WB analysis of U-937 using 19535-1-AP (same clone as 19535-1-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  WB analysis of U-937 using 19535-1-AP (same clone as 19535-1-PBS)

  U-937 cells were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human spleen using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 19535-1-AP (same clone as 19535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 19535-1-AP (same clone as 19535-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

19535-1-PBS bindet in WB, IHC, Indirect ELISA CAPG-Specific und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: capping protein (actin filament), gelsolin-like
• Berechnetes Molekulargewicht: 39 kDa
• Beobachtetes Molekulargewicht: 43 kDa
• GenBank-Zugangsnummer: NM_001747
• Gene symbol: CAPG
• Gene ID (NCBI): 822
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)