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CASZ1 Polyklonaler Antikörper

CASZ1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14534-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CASZ1 Polyclonal antibody (14534-1-AP)

    WB analysis using 14534-1-AP (same clone as 14534-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14534-1-AP (CASZ1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14534-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14534-1-PBS bindet in WB, Indirect ELISA CASZ1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CASZ1 fusion protein Ag6035
Vollständiger Name castor zinc finger 1
Berechnetes Molekulargewicht 190 kDa
Beobachtetes Molekulargewicht150 kDa, 250 kDa
GenBank-ZugangsnummerBC051883
Gene symbol CASZ1
Gene ID (NCBI) 54897
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Zinc finger protein castor homolog 1 (CASZ1), also known as zinc finger protein 693 (ZNF693), belongs to the C2H2-type zinc finger protein family. CASZ1 is a transcription factor that is evolutionarily conserved and participates in multiple embryonic development and physiological processes. CASZ1 has been found to regulate aldosterone synthesis and repress the activation of aldosterone target genes, suggesting that it may participate in blood pressure regulation. CASZ1 is ubiquitously expressed in various embryonic tissues. Subcellularly, CASZ1 is usually localized in the cell nucleus, consistent with its role in transcription regulation (PMID: 37509718). CASZ1 has two isoforms namely CASZ1a (i.e., hcasz11, 190 kDa) and CASZ1b (i.e., hcasz5, 125 kDa). The observed molecular weights were 150 kDa and 250 kDa, respectively, consistent with descriptions in the literature (PMID: 32060262).