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CC2D2A Polyklonaler Antikörper

CC2D2A Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22293-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using CC2D2A Polyclonal antibody (22293-1-AP)

    WB analysis using 22293-1-AP (same clone as 22293-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22293-1-AP (CC2D2A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using CC2D2A Polyclonal antibody (22293-1-AP)

    IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 10x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using CC2D2A Polyclonal antibody (22293-1-AP)

    IHC staining of human lung cancer using 22293-1-AP (same clone as 22293-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer slide using 22293-1-AP (CC2D2A Antibody) at dilution of 1:50(under 40x lens). This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of hTERT-RPE1 cells using CC2D2A Polyclonal antibody (22293-1-AP)

    IF Staining of hTERT-RPE1 cells using 22293-1-AP (same clone as 22293-1-PBS)

    IF result (strong nucleus and the base stain) of anti-CC2D2A (22293-1-AP, 1:50) with serum-starved hTERT-RPE1 (MeOH fixed) by Dr. Moshe Kim. This data was developed using the same antibody clone with 22293-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22293-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA CC2D2A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name coiled-coil and C2 domain containing 2A
Berechnetes Molekulargewicht 186 kDa
Beobachtetes Molekulargewicht 190 kDa
GenBank-ZugangsnummerNM_020785
Gene symbol CC2D2A
Gene ID (NCBI) 57545
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CC2D2A, also named as KIAA1345, may be involved in cilia formation. CC2D2A encodes a protein with similar overall structure to RPGRIP1L, including coiled-coil domains, a C2 domain, and an overlapping centrosomal protein-related domain. CC2D2A physically interacts with CEP290, and loss of Cc2d2a function in the zebrafish sentinel mutant results in abnormal body shape and pronephric (kidney) cysts that is strongly exacerbated by knockdown of Cep290 function. (PMID:19778711 )Defects in CC2D2A are the cause of Meckel syndrome type 6 (MKS6). Defects in CC2D2A are the cause of Joubert syndrome type 9 (JBTS9). The antibody is specific to CC2D2A.