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CCDC23 Polyklonaler Antikörper

CCDC23 Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30688-1-PBS

Synonyme

SVBP, Coiled coil domain-containing protein 23, Small vasohibin-binding protein

Filter:
  • Immunohistochemistry (IHC) staining of mouse skin tissue using CCDC23 Polyclonal antibody (30688-1-AP)

    IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30688-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse skin tissue using CCDC23 Polyclonal antibody (30688-1-AP)

    IHC staining of mouse skin using 30688-1-AP (same clone as 30688-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse skin tissue slide using 30688-1-AP (CCDC23 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30688-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30688-1-PBS bindet in IHC, Indirect ELISA CCDC23 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CCDC23 fusion protein Ag33650
Vollständiger Name coiled-coil domain containing 23
GenBank-ZugangsnummerBC029427
Gene symbol CCDC23
Gene ID (NCBI) 374969
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).