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CCDC85C Polyklonaler Antikörper

CCDC85C Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

Konjugation

Unkonjugiert

Kat-Nr. : 31200-1-PBS

Synonyme

FLJ22558

Filter:
  • Western Blot (WB) analysis of various lysates using CCDC85C Polyclonal antibody (31200-1-AP)

    WB analysis using 31200-1-AP (same clone as 31200-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31200-1-AP (CCDC85C antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31200-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31200-1-PBS bindet in CCDC85C und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen CCDC85C fusion protein Ag35157
Vollständiger Name coiled-coil domain containing 85C
Berechnetes Molekulargewicht419 aa, 45 kDa
Beobachtetes Molekulargewicht45-50 kDa
GenBank-ZugangsnummerNM_001144995
Gene symbol CCDC85C
Gene ID (NCBI) 317762
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ccdc85c (coiled-coil domain containing 85c) is a gene encoding protein, which is located on human chromosome 14 (14q32.2) and belongs to the helical loop domain protein family. The protein is mainly expressed in the neuroepithelial cells of the lateral ventricle wall of the brain, especially at the top junction of radial glial cells. In addition, it is also expressed in a variety of monolayer epithelial cells, but not in stratified epithelial cells. CCDC85C is the pathogenic gene of hereditary hydrocephalus and subcortical endometriosis (often accompanied by cerebral hemorrhage). In CCDC85C gene knockout (KO) mice and rats, abnormal development of ventricular system was observed, resulting in hydrocephalus and cerebral hemorrhage (PMID: 37271245).