CCL1 Rekombinanter Antikörper

CCL1 Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

250094D6

Kat-Nr. : 98502-2-PBS

Synonyme

C-C motif chemokine 1, P500, Scya1, SIS-epsilon, Small-inducible cytokine A1

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  FC experiment of Transfected HEK-293T using 98502-2-RR (same clone as 98502-2-PBS)

  1x10^6 HEK-293T cells or CCL1-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL1 Rabbit RecAb (98502-2-RR, Clone: 250094D6) and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98502-2-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98502-2-RR (same clone as 98502-2-PBS)

  1x10^6 HEK-293T cells or CCL1-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL1 Rabbit RecAb (98502-2-RR, Clone: 250094D6) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and APC-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98502-2-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98502-2-PBS bindet in FC (Intra) CCL1 und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CCL1 fusion protein Eg3293
• Vollständiger Name: chemokine (C-C motif) ligand 1
• Berechnetes Molekulargewicht: 10KD
• GenBank-Zugangsnummer: NM_011329.3
• Gene symbol: Ccl1
• Gene ID (NCBI): 20290
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CCL1, also known as I-309 in human or TCA-3 in mice, is a small glycoprotein belonging to the CC chemokine family. It is predominantly expressed by activated T cells, monocytes, and endothelial cells, and primarily acts as a chemoattractant for monocytes and T cells. CCL1 binds to the receptor CCR8, which is expressed on monocytes, neutrophils, and T cells, including within the thymus. This chemokine may perform dual functions: as an inflammatory chemokine during leukocyte migration into inflammatory sites and as a constitutive chemokine during T cell selection in the thymus. Furthermore, CCL1 has been associated with allergic inflammation and the recruitment of Th2 cells, suggesting a role in allergic diseases such as asthma.