CCL17/TARC Rekombinanter Antikörper

CCL17/TARC Rekombinant Antikörper für FC (Intra)

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

Maus

Anwendung

FC (Intra)

Konjugation

Unkonjugiert

CloneNo.

250385D10

Kat-Nr. : 98553-1-PBS

Synonyme

ABCD-2, CC chemokine TARC, C-C motif chemokine 17, Ccl17, Small-inducible cytokine A17

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  FC experiment of Transfected HEK-293T using 98553-1-RR (same clone as 98553-1-PBS)

  1x10^6 HEK-293T cells or CCL17/TARC-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL17/TARC Rabbit RecAb (98553-1-RR, Clone: 250385D10) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98553-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98553-1-RR (same clone as 98553-1-PBS)

  1x10^6 HEK-293T cells or CCL17/TARC-transfected HEK-293T cells were intracellularly stained with 0.25 ug Anti-Mouse CCL17/TARC Rabbit RecAb (98553-1-RR, Clone: 250385D10) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98553-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98553-1-PBS bindet in FC (Intra) CCL17/TARC und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: CCL17/TARC fusion protein Eg3319
• Vollständiger Name: chemokine (C-C motif) ligand 17
• Berechnetes Molekulargewicht: 11 kDa
• GenBank-Zugangsnummer: NM_011332.3
• Gene symbol: Ccl17
• Gene ID (NCBI): 20295
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

CCL17, also named as TARC, is a member of the CC chemokine family, and is highly expressed by thymus and other cells, including keratinocytes, endothelial cells, dendritic cells, bronchial epithelial cells and fibroblasts. CCL17 plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. CCL17 induced chemotaxis and Ca2+ influx in the cells stably expressing CCR4, thereby demonstrating the ligand-receptor relationship between CCL17 and CCR4.